It would be very useful to be able to create different debug profiles for one project.
Now you have to copy the project and set up debug in each one, which is very inconvenient.

I have v20 now. I'm planning to update. Maybe in v21 already has it?

Can you clarify which debugger settings you’d like to configure in these profiles under a single project?
Additionally, how would you prefer to select the specific profile to use?
Lastly, could you explain why a single set of debugger settings isn’t sufficient for your situation?
Sharing more details about your specific use case or the challenges you’re encountering would help me better understand and think through potential solutions.