Hi,
I'm having trouble having the PhpEd debugger/profiler work with zend optimizer. I looked into the messages in the forum and made necessary changes. Here are the details of my set up. If I can get the profiler working, it will really help me.

1. A small script with <?php phpinfo() ?> is accessed and the snapshots are attached. (a) phpver (b) debugger

2. I've added the following lines to C:\Programs\xampp\apache\bin\php.ini

[debugger]
zend_extension_ts="C:\Program Files\nusphere\phped\debugger\server\Win32\x86\php_dbg.dll-5.2.x"

[Zend]
zend_optimizer.optimization_level=15
zend_extension_ts="C:\Program Files\Zend\ZendOptimizer-3.2.2\lib\Optimizer-3.2.2\php-5.2.x\ZendOptimizer.dll"

Is there something I'm missing?

Thanks,
Srini

One more bit of info, when http://localhost/myphpinfo.php is invoked from a browser, I see that zend optimizer is listed. But when I invoke the same from PhpEd IDE, zend optimizer doesn't show up.

I do not see any problems.
When you say you run it from the IDE, do you mean you run php that comes with phped or php that you installed with zend optimizer? In the first case, it's absolutely okay to see no optimizers because it does not come with the IDE.
In order to work with web server that is installed by you, you need to set Run Mode to 3rd party web server. See project properties.